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The synthesis of tirzepatide was first disclosed in patents filed by Eli Lilly and Enterprise.[35] This uses conventional solid stage peptide synthesis, by having an allyloxycarbonyl protecting group on the lysine at situation 20 on the linear chain of amino acids, permitting a final set of chemical
NAION occurs when the optic nerve head, in which the retina and optic nerve connect, experiences constriction and swelling. Eventually, this may cause mobile Demise while in the retina resulting from insufficient blood movement, leading to eyesight loss. Usually just one eye is affected.
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